Searchable abstracts of presentations at key conferences in endocrinology

ea0026p259 | Pituitary | ECE2011

Predictive markers of recurrence in radically resected pituitary macroadenomas

Curto L , Ruggeri R M , Cotta O R , Ragonese M , Ieni A , Puglisi S , Costanzo D , Trimarchi F , Cannavo Salvatore

Introduction: Pituitary adenomas are benign neoplasms which grow slowly, but that can recur even after apparent radical resection. Until now, markers predicting regrowth and invasiveness have not been completely characterized.Design: We investigated cell proliferation and apoptosis parameters in 20 radically resected pituitary macroadenomas (six GH, two PRL, two ACTH, one FSH and nine non-secreting), in order to predict recurrence risk. Tumour regrowth w...